T508-0074 Screening compound: 8-(4-ethylpiperazine-1-carbonyl)-7-phenyl-1,2,3,5-tetrahydroindolizin-5-one

T508-0074 Screening compound: 8-(4-ethylpiperazine-1-carbonyl)-7-phenyl-1,2,3,5-tetrahydroindolizin-5-one
T508-0074 Screening compound: 8-(4-ethylpiperazine-1-carbonyl)-7-phenyl-1,2,3,5-tetrahydroindolizin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T508-0074
8-(4-ethylpiperazine-1-carbonyl)-7-phenyl-1,2,3,5-tetrahydroindolizin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T508-0074

Molecular Formula

C21H25N3O2 (C21 H25 N3 O2)

Compound Name

8-(4-ethylpiperazine-1-carbonyl)-7-phenyl-1,2,3,5-tetrahydroindolizin-5-one

IUPAC name

8-(4-ethylpiperazine-1-carbonyl)-7-phenyl-1235-tetrahydroindolizin-5-one

SMILES

CCN(CC1)CCN1C(C(C(c1ccccc1)=C1)=C(CCC2)N2C1=O)=O

InChI

InChI=1S/C21H25N3O2/c1-2-22-11-13-23(14-12-22)21(26)20-17(16-7-4-3-5-8-16)15-19(25)24-10-6-9-18(20)24/h3-5,7-8,15H,2,6,9-14H2,1H3

InChI Key

AOSIBNUKDMTXEI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31973316

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.551

Distribution Coefficient, logD

1.327

Water Solubility, LogSw

-1.93

Polar Surface Area

37.279

Acid Dissociation Constant (pKa)

23.13

Base Dissociation Constant (pKb)

7.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.86

T508-0074 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

CNS BBB Library (22607 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Nervous system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T508-0074 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T508-0074?
Check Price and Availability of T508-0074, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T508-0074 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T508-0074
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T508-0074
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T508-0074 available by request