T579-1486 Screening compound: 5-{[4-(1H-INDOLE-3-CARBONYL)PIPERAZIN-1-YL]METHYL}-1-METHYL-1,2-DIHYDROPYRIDIN-2-ONE

T579-1486 Screening compound: 5-{[4-(1H-INDOLE-3-CARBONYL)PIPERAZIN-1-YL]METHYL}-1-METHYL-1,2-DIHYDROPYRIDIN-2-ONE
T579-1486 Screening compound: 5-{[4-(1H-INDOLE-3-CARBONYL)PIPERAZIN-1-YL]METHYL}-1-METHYL-1,2-DIHYDROPYRIDIN-2-ONE alternative view

Chemical Structure Depiction of ChemDiv screening compound T579-1486
5-{[4-(1H-INDOLE-3-CARBONYL)PIPERAZIN-1-YL]METHYL}-1-METHYL-1,2-DIHYDROPYRIDIN-2-ONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T579-1486

Molecular Formula

C20H22N4O2 (C20 H22 N4 O2)

Compound Name

5-{[4-(1H-INDOLE-3-CARBONYL)PIPERAZIN-1-YL]METHYL}-1-METHYL-1,2-DIHYDROPYRIDIN-2-ONE

IUPAC name

n/a

SMILES

CN(C=C(CN(CC1)CCN1C(c1c[nH]c2c1cccc2)=O)C=C1)C1=O

InChI

InChI=1S/C20H22N4O2/c1-22-13-15(6-7-19(22)25)14-23-8-10-24(11-9-23)20(26)17-12-21-18-5-3-2-4-16(17)18/h2-7,12-13,21H,8-11,14H2,1H3

InChI Key

BRLNSRQKEPDELI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29027813

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.709

Distribution Coefficient, logD

0.702

Water Solubility, LogSw

-2.23

Polar Surface Area

46.796

Acid Dissociation Constant (pKa)

17.30

Base Dissociation Constant (pKb)

5.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

T579-1486 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Indole Derivatives (10091 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Structure:
  • Cyclic compounds
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with T579-1486 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T579-1486?
Check Price and Availability of T579-1486, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T579-1486 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T579-1486
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T579-1486
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T579-1486 available by request