T619-4754 Screening compound: 4-{5-[1-(1-ethyl-1H-pyrazole-3-carbonyl)piperidin-2-yl]-1,2,4-oxadiazol-3-yl}pyridine

T619-4754 Screening compound: 4-{5-[1-(1-ethyl-1H-pyrazole-3-carbonyl)piperidin-2-yl]-1,2,4-oxadiazol-3-yl}pyridine
T619-4754 Screening compound: 4-{5-[1-(1-ethyl-1H-pyrazole-3-carbonyl)piperidin-2-yl]-1,2,4-oxadiazol-3-yl}pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound T619-4754
4-{5-[1-(1-ethyl-1H-pyrazole-3-carbonyl)piperidin-2-yl]-1,2,4-oxadiazol-3-yl}pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T619-4754

Molecular Formula

C18H20N6O2 (C18 H20 N6 O2)

Compound Name

4-{5-[1-(1-ethyl-1H-pyrazole-3-carbonyl)piperidin-2-yl]-1,2,4-oxadiazol-3-yl}pyridine

IUPAC name

4-{5-[1-(1-ethyl-1H-pyrazole-3-carbonyl)piperidin-2-yl]-124-oxadiazol-3-yl}pyridine

SMILES

CCn(cc1)nc1C(N(CCCC1)C1c1nc(-c2ccncc2)no1)=O

InChI

InChI=1S/C18H20N6O2/c1-2-23-12-8-14(21-23)18(25)24-11-4-3-5-15(24)17-20-16(22-26-17)13-6-9-19-10-7-13/h6-10,12,15H,2-5,11H2,1H3/t15-/m0/s1

InChI Key

HTSHTDNDXRQPDV-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD29027856

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

352.4

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.032

Distribution Coefficient, logD

2.032

Water Solubility, LogSw

-1.74

Polar Surface Area

71.800

Acid Dissociation Constant (pKa)

26.92

Base Dissociation Constant (pKb)

3.68

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.90

T619-4754 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T619-4754 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T619-4754?
Check Price and Availability of T619-4754, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T619-4754 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T619-4754
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T619-4754
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T619-4754 available by request