T619-4826 Screening compound: 4-{5-[1-(5-methylthiophene-2-carbonyl)piperidin-2-yl]-1,2,4-oxadiazol-3-yl}pyridine

T619-4826 Screening compound: 4-{5-[1-(5-methylthiophene-2-carbonyl)piperidin-2-yl]-1,2,4-oxadiazol-3-yl}pyridine
T619-4826 Screening compound: 4-{5-[1-(5-methylthiophene-2-carbonyl)piperidin-2-yl]-1,2,4-oxadiazol-3-yl}pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound T619-4826
4-{5-[1-(5-methylthiophene-2-carbonyl)piperidin-2-yl]-1,2,4-oxadiazol-3-yl}pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T619-4826

Molecular Formula

C18H18N4O2S (C18 H18 N4 O2 S)

Compound Name

4-{5-[1-(5-methylthiophene-2-carbonyl)piperidin-2-yl]-1,2,4-oxadiazol-3-yl}pyridine

IUPAC name

4-{5-[1-(5-methylthiophene-2-carbonyl)piperidin-2-yl]-124-oxadiazol-3-yl}pyridine

SMILES

Cc1ccc(C(N(CCCC2)C2c2nc(-c3ccncc3)no2)=O)s1

InChI

InChI=1S/C18H18N4O2S/c1-12-5-6-15(25-12)18(23)22-11-3-2-4-14(22)17-20-16(21-24-17)13-7-9-19-10-8-13/h5-10,14H,2-4,11H2,1H3/t14-/m0/s1

InChI Key

BHSWMVIQZXDNNI-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD29027863

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.870

Distribution Coefficient, logD

3.870

Water Solubility, LogSw

-3.71

Polar Surface Area

58.433

Acid Dissociation Constant (pKa)

27.41

Base Dissociation Constant (pKb)

3.68

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

T619-4826 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T619-4826 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T619-4826?
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What is the minimum amount of T619-4826 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T619-4826
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T619-4826
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T619-4826 available by request