T626-1476 Screening compound: 5,6-dimethyl-2-(pyrazin-2-yl)-3,4-dihydropyrimidin-4-one

T626-1476 Screening compound: 5,6-dimethyl-2-(pyrazin-2-yl)-3,4-dihydropyrimidin-4-one
T626-1476 Screening compound: 5,6-dimethyl-2-(pyrazin-2-yl)-3,4-dihydropyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T626-1476
5,6-dimethyl-2-(pyrazin-2-yl)-3,4-dihydropyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T626-1476

Molecular Formula

C10H10N4O (C10 H10 N4 O)

Compound Name

5,6-dimethyl-2-(pyrazin-2-yl)-3,4-dihydropyrimidin-4-one

IUPAC name

56-dimethyl-2-(pyrazin-2-yl)-34-dihydropyrimidin-4-one

SMILES

CC1=C(C)N=C(c2nccnc2)NC1=O

InChI

InChI=1S/C10H10N4O/c1-6-7(2)13-9(14-10(6)15)8-5-11-3-4-12-8/h3-5H,1-2H3,(H,13,14,15)

InChI Key

UJRFQHPLFDUJSV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD12817513

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

202.22

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

-0.137

Distribution Coefficient, logD

-1.230

Water Solubility, LogSw

-1.59

Polar Surface Area

53.108

Acid Dissociation Constant (pKa)

6.34

Base Dissociation Constant (pKb)

4.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

T626-1476 in Drug Discovery

Included in Screening Libraries

Fragments Library (11262 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Structure:
  • Fragments
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with T626-1476 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T626-1476?
Check Price and Availability of T626-1476, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T626-1476 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T626-1476
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T626-1476
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T626-1476 available by request