T633-1680 Screening compound: 1-[3-(4-ethyl-4H-1,2,4-triazol-3-yl)piperidin-1-yl]-3-(1H-indol-3-yl)propan-1-one

T633-1680 Screening compound: 1-[3-(4-ethyl-4H-1,2,4-triazol-3-yl)piperidin-1-yl]-3-(1H-indol-3-yl)propan-1-one
T633-1680 Screening compound: 1-[3-(4-ethyl-4H-1,2,4-triazol-3-yl)piperidin-1-yl]-3-(1H-indol-3-yl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T633-1680
1-[3-(4-ethyl-4H-1,2,4-triazol-3-yl)piperidin-1-yl]-3-(1H-indol-3-yl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T633-1680

Molecular Formula

C20H25N5O (C20 H25 N5 O)

Compound Name

1-[3-(4-ethyl-4H-1,2,4-triazol-3-yl)piperidin-1-yl]-3-(1H-indol-3-yl)propan-1-one

IUPAC name

1-[3-(4-ethyl-4H-124-triazol-3-yl)piperidin-1-yl]-3-(1H-indol-3-yl)propan-1-one

SMILES

CCn1c(C(CCC2)CN2C(CCc2c[nH]c3c2cccc3)=O)nnc1

InChI

InChI=1S/C20H25N5O/c1-2-24-14-22-23-20(24)16-6-5-11-25(13-16)19(26)10-9-15-12-21-18-8-4-3-7-17(15)18/h3-4,7-8,12,14,16,21H,2,5-6,9-11,13H2,1H3/t16-/m0/s1

InChI Key

DWWGRPJVWMQOAP-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27622747

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.959

Distribution Coefficient, logD

1.957

Water Solubility, LogSw

-2.32

Polar Surface Area

50.245

Acid Dissociation Constant (pKa)

17.92

Base Dissociation Constant (pKb)

7.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.00

T633-1680 in Drug Discovery

Included in Screening Libraries

Indole Derivatives (10091 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

SmartTM Library (51161 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer

References: we are preparing a list of scientific research reports with T633-1680 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T633-1680?
Check Price and Availability of T633-1680, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T633-1680 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T633-1680
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T633-1680
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T633-1680 available by request