T636-1196 Screening compound: N-(1-{5H,6H,7H-cyclopenta[d]pyrimidin-4-yl}pyrrolidin-3-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide

T636-1196 Screening compound: N-(1-{5H,6H,7H-cyclopenta[d]pyrimidin-4-yl}pyrrolidin-3-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide
T636-1196 Screening compound: N-(1-{5H,6H,7H-cyclopenta[d]pyrimidin-4-yl}pyrrolidin-3-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T636-1196
N-(1-{5H,6H,7H-cyclopenta[d]pyrimidin-4-yl}pyrrolidin-3-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T636-1196

Molecular Formula

C17H22N6O (C17 H22 N6 O)

Compound Name

N-(1-{5H,6H,7H-cyclopenta[d]pyrimidin-4-yl}pyrrolidin-3-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide

IUPAC name

N-(1-{5H6H7H-cyclopenta[d]pyrimidin-4-yl}pyrrolidin-3-yl)-15-dimethyl-1H-pyrazole-3-carboxamide

SMILES

Cc1cc(C(NC(CC2)CN2c2ncnc3c2CCC3)=O)nn1C

InChI

InChI=1S/C17H22N6O/c1-11-8-15(21-22(11)2)17(24)20-12-6-7-23(9-12)16-13-4-3-5-14(13)18-10-19-16/h8,10,12H,3-7,9H2,1-2H3,(H,20,24)/t12-/m0/s1

InChI Key

OZLSZSHFTNKOFG-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD27622931

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

326.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.250

Distribution Coefficient, logD

1.230

Water Solubility, LogSw

-2.03

Polar Surface Area

63.954

Acid Dissociation Constant (pKa)

14.87

Base Dissociation Constant (pKb)

6.08

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.90

T636-1196 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with T636-1196 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T636-1196?
Check Price and Availability of T636-1196, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T636-1196 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T636-1196
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T636-1196
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T636-1196 available by request