T636-2424 Screening compound: 1-[3-(6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)-1-pyrrolidinyl]-2-(3,5-dimethyl-4-isoxazolyl)-1-ethanone

T636-2424 Screening compound: 1-[3-(6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)-1-pyrrolidinyl]-2-(3,5-dimethyl-4-isoxazolyl)-1-ethanone
T636-2424 Screening compound: 1-[3-(6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)-1-pyrrolidinyl]-2-(3,5-dimethyl-4-isoxazolyl)-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound T636-2424
1-[3-(6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)-1-pyrrolidinyl]-2-(3,5-dimethyl-4-isoxazolyl)-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T636-2424

Molecular Formula

C18H23N5O2 (C18 H23 N5 O2)

Compound Name

1-[3-(6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)-1-pyrrolidinyl]-2-(3,5-dimethyl-4-isoxazolyl)-1-ethanone

IUPAC name

1-[3-({5H6H7H-cyclopenta[d]pyrimidin-4-yl}amino)pyrrolidin-1-yl]-2-(35-dimethyl-12-oxazol-4-yl)ethan-1-one

SMILES

Cc1noc(C)c1CC(N(CC1)CC1Nc1ncnc2c1CCC2)=O

InChI

InChI=1S/C18H23N5O2/c1-11-15(12(2)25-22-11)8-17(24)23-7-6-13(9-23)21-18-14-4-3-5-16(14)19-10-20-18/h10,13H,3-9H2,1-2H3,(H,19,20,21)/t13-/m1/s1

InChI Key

HZQSPKWQULVXKJ-CYBMUJFWSA-N

MDL Number (MFCD)

MFCD27623049

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

341.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.701

Distribution Coefficient, logD

1.696

Water Solubility, LogSw

-2.05

Polar Surface Area

70.702

Acid Dissociation Constant (pKa)

14.17

Base Dissociation Constant (pKb)

5.41

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

55.56

T636-2424 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T636-2424 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T636-2424?
Check Price and Availability of T636-2424, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T636-2424 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T636-2424
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T636-2424
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T636-2424 available by request