T651-0350 Screening compound: N-{(1R,5S)-8-[(4-METHYL-3-PYRIDYL)CARBONYL]-8-AZABICYCLO[3.2.1]OCT-3-YL}ISONICOTINAMIDE

T651-0350 Screening compound: N-{(1R,5S)-8-[(4-METHYL-3-PYRIDYL)CARBONYL]-8-AZABICYCLO[3.2.1]OCT-3-YL}ISONICOTINAMIDE
T651-0350 Screening compound: N-{(1R,5S)-8-[(4-METHYL-3-PYRIDYL)CARBONYL]-8-AZABICYCLO[3.2.1]OCT-3-YL}ISONICOTINAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound T651-0350
N-{(1R,5S)-8-[(4-METHYL-3-PYRIDYL)CARBONYL]-8-AZABICYCLO[3.2.1]OCT-3-YL}ISONICOTINAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T651-0350

Molecular Formula

C20H22N4O2 (C20 H22 N4 O2)

Compound Name

N-{(1R,5S)-8-[(4-METHYL-3-PYRIDYL)CARBONYL]-8-AZABICYCLO[3.2.1]OCT-3-YL}ISONICOTINAMIDE

IUPAC name

n/a

SMILES

Cc(ccnc1)c1C(N([C@H](CC1)C2)[C@@H]1CC2NC(c1ccncc1)=O)=O

InChI

InChI=1S/C20H22N4O2/c1-13-4-7-22-12-18(13)20(26)24-16-2-3-17(24)11-15(10-16)23-19(25)14-5-8-21-9-6-14/h4-9,12,15-17H,2-3,10-11H2,1H3,(H,23,25)/t15?,16-,17+

InChI Key

QBMYLXKIKWWXTP-ALOPSCKCSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.432

Distribution Coefficient, logD

0.432

Water Solubility, LogSw

-1.14

Polar Surface Area

58.651

Acid Dissociation Constant (pKa)

12.78

Base Dissociation Constant (pKb)

4.39

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

40.00

T651-0350 in Drug Discovery

Included in Screening Libraries

Bromodomain Modulators Library (5801 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
Targets:
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T651-0350 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T651-0350?
Check Price and Availability of T651-0350, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T651-0350 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T651-0350
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T651-0350
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T651-0350 available by request