T654-0310 Screening compound: 3-(3,5-dimethyl-1H-pyrazol-1-yl)-1-[2-(5-tetrahydro-2H-pyran-4-yl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-indol-1-yl]-1-propanone

T654-0310 Screening compound: 3-(3,5-dimethyl-1H-pyrazol-1-yl)-1-[2-(5-tetrahydro-2H-pyran-4-yl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-indol-1-yl]-1-propanone
T654-0310 Screening compound: 3-(3,5-dimethyl-1H-pyrazol-1-yl)-1-[2-(5-tetrahydro-2H-pyran-4-yl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-indol-1-yl]-1-propanone alternative view

Chemical Structure Depiction of ChemDiv screening compound T654-0310
3-(3,5-dimethyl-1H-pyrazol-1-yl)-1-[2-(5-tetrahydro-2H-pyran-4-yl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-indol-1-yl]-1-propanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T654-0310

Molecular Formula

C23H27N5O3 (C23 H27 N5 O3)

Compound Name

3-(3,5-dimethyl-1H-pyrazol-1-yl)-1-[2-(5-tetrahydro-2H-pyran-4-yl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-indol-1-yl]-1-propanone

IUPAC name

n/a

SMILES

Cc1cc(C)nn1CCC(N(C(C1)c2noc(C3CCOCC3)n2)c2c1cccc2)=O

InChI

InChI=1S/C23H27N5O3/c1-15-13-16(2)27(25-15)10-7-21(29)28-19-6-4-3-5-18(19)14-20(28)22-24-23(31-26-22)17-8-11-30-12-9-17/h3-6,13,17,20H,7-12,14H2,1-2H3/t20-/m0/s1

InChI Key

WSQMUIFZOKFSRX-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD29002472

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.625

Distribution Coefficient, logD

2.625

Water Solubility, LogSw

-2.81

Polar Surface Area

68.230

Acid Dissociation Constant (pKa)

21.63

Base Dissociation Constant (pKb)

2.75

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

47.80

T654-0310 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • Epigenetic
Structure:
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with T654-0310 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T654-0310?
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What is the minimum amount of T654-0310 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T654-0310
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T654-0310
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T654-0310 available by request