T655-0355 Screening compound: 2-(pyrazine-2-carbonyl)-4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decane

T655-0355 Screening compound: 2-(pyrazine-2-carbonyl)-4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decane
T655-0355 Screening compound: 2-(pyrazine-2-carbonyl)-4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound T655-0355
2-(pyrazine-2-carbonyl)-4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T655-0355

Molecular Formula

C20H20N6O3 (C20 H20 N6 O3)

Compound Name

2-(pyrazine-2-carbonyl)-4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decane

IUPAC name

2-(pyrazine-2-carbonyl)-4-[5-(pyridin-4-yl)-134-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decane

SMILES

O=C(c1nccnc1)N(C1)CC2(CCOCC2)C1c1nnc(-c2ccncc2)o1

InChI

InChI=1S/C20H20N6O3/c27-19(16-11-22-7-8-23-16)26-12-15(20(13-26)3-9-28-10-4-20)18-25-24-17(29-18)14-1-5-21-6-2-14/h1-2,5-8,11,15H,3-4,9-10,12-13H2/t15-/m0/s1

InChI Key

OUQMGIUMYAHLIN-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD29002524

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.42

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.238

Distribution Coefficient, logD

0.238

Water Solubility, LogSw

-0.64

Polar Surface Area

83.187

Acid Dissociation Constant (pKa)

26.21

Base Dissociation Constant (pKb)

4.57

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.00

T655-0355 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Peptidomimetics of Beta-Turn Motifs Library (2153 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with T655-0355 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T655-0355?
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What is the minimum amount of T655-0355 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T655-0355
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T655-0355
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T655-0355 available by request