T655-0364 Screening compound: 4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-2-(thiophene-2-sulfonyl)-8-oxa-2-azaspiro[4.5]decane

T655-0364 Screening compound: 4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-2-(thiophene-2-sulfonyl)-8-oxa-2-azaspiro[4.5]decane
T655-0364 Screening compound: 4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-2-(thiophene-2-sulfonyl)-8-oxa-2-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound T655-0364
4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-2-(thiophene-2-sulfonyl)-8-oxa-2-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T655-0364

Molecular Formula

C19H20N4O4S2 (C19 H20 N4 O4 S2)

Compound Name

4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-2-(thiophene-2-sulfonyl)-8-oxa-2-azaspiro[4.5]decane

IUPAC name

4-[5-(pyridin-4-yl)-134-oxadiazol-2-yl]-2-(thiophene-2-sulfonyl)-8-oxa-2-azaspiro[4.5]decane

SMILES

O=S(c1cccs1)(N(C1)CC2(CCOCC2)C1c1nnc(-c2ccncc2)o1)=O

InChI

InChI=1S/C19H20N4O4S2/c24-29(25,16-2-1-11-28-16)23-12-15(19(13-23)5-9-26-10-6-19)18-22-21-17(27-18)14-3-7-20-8-4-14/h1-4,7-8,11,15H,5-6,9-10,12-13H2/t15-/m0/s1

InChI Key

YTYBCLHFJCJSKO-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD29002530

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.52

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.645

Distribution Coefficient, logD

1.645

Water Solubility, LogSw

-2.02

Polar Surface Area

80.702

Acid Dissociation Constant (pKa)

27.26

Base Dissociation Constant (pKb)

4.57

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.10

T655-0364 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T655-0364 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T655-0364?
Check Price and Availability of T655-0364, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T655-0364 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T655-0364
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T655-0364
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T655-0364 available by request