T655-0650 Screening compound: ethyl 3-({4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decane-2-carbonyl}amino)propanoate

T655-0650 Screening compound: ethyl 3-({4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decane-2-carbonyl}amino)propanoate
T655-0650 Screening compound: ethyl 3-({4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decane-2-carbonyl}amino)propanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound T655-0650
ethyl 3-({4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decane-2-carbonyl}amino)propanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T655-0650

Molecular Formula

C21H27N5O5 (C21 H27 N5 O5)

Compound Name

ethyl 3-({4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decane-2-carbonyl}amino)propanoate

IUPAC name

ethyl 3-({4-[5-(pyridin-4-yl)-134-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decane-2-carbonyl}amino)propanoate

SMILES

CCOC(CCNC(N(C1)CC2(CCOCC2)C1c1nnc(-c2ccncc2)o1)=O)=O

InChI

InChI=1S/C21H27N5O5/c1-2-30-17(27)5-10-23-20(28)26-13-16(21(14-26)6-11-29-12-7-21)19-25-24-18(31-19)15-3-8-22-9-4-15/h3-4,8-9,16H,2,5-7,10-14H2,1H3,(H,23,28)/t16-/m0/s1

InChI Key

FSCNTZJBHOLTHW-INIZCTEOSA-N

MDL Number (MFCD)

MFCD29004267

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.48

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.938

Distribution Coefficient, logD

0.937

Water Solubility, LogSw

-1.41

Polar Surface Area

95.036

Acid Dissociation Constant (pKa)

16.46

Base Dissociation Constant (pKb)

4.57

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

57.10

T655-0650 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Peptidomimetics of Beta-Turn Motifs Library (2153 compounds)

Peptidomimetic Library (37031 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with T655-0650 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T655-0650?
Check Price and Availability of T655-0650, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T655-0650 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T655-0650
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T655-0650
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T655-0650 available by request