T746-0960 Screening compound: 2-[6,7-dimethyl-5-oxo-2,3-dihydroimidazo[1,2-a]pyrimidin-1(5H)-yl]-N~1~-(2-thienylmethyl)acetamide

T746-0960 Screening compound: 2-[6,7-dimethyl-5-oxo-2,3-dihydroimidazo[1,2-a]pyrimidin-1(5H)-yl]-N~1~-(2-thienylmethyl)acetamide
T746-0960 Screening compound: 2-[6,7-dimethyl-5-oxo-2,3-dihydroimidazo[1,2-a]pyrimidin-1(5H)-yl]-N~1~-(2-thienylmethyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T746-0960
2-[6,7-dimethyl-5-oxo-2,3-dihydroimidazo[1,2-a]pyrimidin-1(5H)-yl]-N~1~-(2-thienylmethyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T746-0960

Molecular Formula

C15H18N4O2S (C15 H18 N4 O2 S)

Compound Name

2-[6,7-dimethyl-5-oxo-2,3-dihydroimidazo[1,2-a]pyrimidin-1(5H)-yl]-N~1~-(2-thienylmethyl)acetamide

IUPAC name

2-{67-dimethyl-5-oxo-1H2H3H5H-imidazo[12-a]pyrimidin-1-yl}-N-[(thiophen-2-yl)methyl]acetamide

SMILES

CC1=C(C)N=C(N(CC(NCc2cccs2)=O)CC2)N2C1=O

InChI

InChI=1S/C15H18N4O2S/c1-10-11(2)17-15-18(5-6-19(15)14(10)21)9-13(20)16-8-12-4-3-7-22-12/h3-4,7H,5-6,8-9H2,1-2H3,(H,16,20)

InChI Key

PUNQTZGBDNFFPT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27623298

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

318.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.815

Distribution Coefficient, logD

0.815

Water Solubility, LogSw

-2.06

Polar Surface Area

55.432

Acid Dissociation Constant (pKa)

14.11

Base Dissociation Constant (pKb)

2.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

T746-0960 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T746-0960 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T746-0960?
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What is the minimum amount of T746-0960 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T746-0960
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T746-0960
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T746-0960 available by request