T815-0352 Screening compound: 3-phenyl-7-{pyrazolo[1,5-a]pyrimidine-3-carbonyl}-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine

T815-0352 Screening compound: 3-phenyl-7-{pyrazolo[1,5-a]pyrimidine-3-carbonyl}-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine
T815-0352 Screening compound: 3-phenyl-7-{pyrazolo[1,5-a]pyrimidine-3-carbonyl}-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine alternative view

Chemical Structure Depiction of ChemDiv screening compound T815-0352
3-phenyl-7-{pyrazolo[1,5-a]pyrimidine-3-carbonyl}-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T815-0352

Molecular Formula

C18H15N7O (C18 H15 N7 O)

Compound Name

3-phenyl-7-{pyrazolo[1,5-a]pyrimidine-3-carbonyl}-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine

IUPAC name

3-phenyl-7-{pyrazolo[15-a]pyrimidine-3-carbonyl}-5H6H7H8H-[124]triazolo[43-a]pyrazine

SMILES

O=C(c1c2ncccn2nc1)N1Cc2nnc(-c3ccccc3)n2CC1

InChI

InChI=1S/C18H15N7O/c26-18(14-11-20-25-8-4-7-19-17(14)25)23-9-10-24-15(12-23)21-22-16(24)13-5-2-1-3-6-13/h1-8,11H,9-10,12H2

InChI Key

APFVIBYHRMZBKQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29027554

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

345.36

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.406

Distribution Coefficient, logD

0.406

Water Solubility, LogSw

-1.91

Polar Surface Area

62.326

Acid Dissociation Constant (pKa)

19.02

Base Dissociation Constant (pKb)

1.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

T815-0352 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

TLR-8 ligands Library (674 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Female
  • Skin
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Targets:
  • Others
  • Others
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T815-0352 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T815-0352?
Check Price and Availability of T815-0352, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T815-0352 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T815-0352
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T815-0352
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T815-0352 available by request