T828-1648 Screening compound: N,N-diethyl-6-[4-(4-methylphenyl)piperazine-1-carbonyl]-5,6,7,8-tetrahydroquinazolin-2-amine

T828-1648 Screening compound: N,N-diethyl-6-[4-(4-methylphenyl)piperazine-1-carbonyl]-5,6,7,8-tetrahydroquinazolin-2-amine
T828-1648 Screening compound: N,N-diethyl-6-[4-(4-methylphenyl)piperazine-1-carbonyl]-5,6,7,8-tetrahydroquinazolin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound T828-1648
N,N-diethyl-6-[4-(4-methylphenyl)piperazine-1-carbonyl]-5,6,7,8-tetrahydroquinazolin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T828-1648

Molecular Formula

C24H33N5O (C24 H33 N5 O)

Compound Name

N,N-diethyl-6-[4-(4-methylphenyl)piperazine-1-carbonyl]-5,6,7,8-tetrahydroquinazolin-2-amine

IUPAC name

NN-diethyl-6-[4-(4-methylphenyl)piperazine-1-carbonyl]-5678-tetrahydroquinazolin-2-amine

SMILES

CCN(CC)c1nc(CCC(C2)C(N(CC3)CCN3c3ccc(C)cc3)=O)c2cn1

InChI

InChI=1S/C24H33N5O/c1-4-27(5-2)24-25-17-20-16-19(8-11-22(20)26-24)23(30)29-14-12-28(13-15-29)21-9-6-18(3)7-10-21/h6-7,9-10,17,19H,4-5,8,11-16H2,1-3H3/t19-/m0/s1

InChI Key

NTPXPKYHKKCYKU-IBGZPJMESA-N

MDL Number (MFCD)

MFCD27624075

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.56

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.905

Distribution Coefficient, logD

3.902

Water Solubility, LogSw

-3.74

Polar Surface Area

42.325

Acid Dissociation Constant (pKa)

19.85

Base Dissociation Constant (pKb)

5.27

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

54.20

T828-1648 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T828-1648 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T828-1648?
Check Price and Availability of T828-1648, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T828-1648 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T828-1648
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T828-1648
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T828-1648 available by request