T829-1492 Screening compound: 1-{5-[(4-fluorophenyl)methyl]-2-methyl-4H,5H,6H,7H-furo[3,2-c]pyridine-3-carbonyl}-4-phenylpiperazine

T829-1492 Screening compound: 1-{5-[(4-fluorophenyl)methyl]-2-methyl-4H,5H,6H,7H-furo[3,2-c]pyridine-3-carbonyl}-4-phenylpiperazine
T829-1492 Screening compound: 1-{5-[(4-fluorophenyl)methyl]-2-methyl-4H,5H,6H,7H-furo[3,2-c]pyridine-3-carbonyl}-4-phenylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound T829-1492
1-{5-[(4-fluorophenyl)methyl]-2-methyl-4H,5H,6H,7H-furo[3,2-c]pyridine-3-carbonyl}-4-phenylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T829-1492

Molecular Formula

C26H28FN3O2 (C26 H28 FN3 O2)

Compound Name

1-{5-[(4-fluorophenyl)methyl]-2-methyl-4H,5H,6H,7H-furo[3,2-c]pyridine-3-carbonyl}-4-phenylpiperazine

IUPAC name

1-{5-[(4-fluorophenyl)methyl]-2-methyl-4H5H6H7H-furo[32-c]pyridine-3-carbonyl}-4-phenylpiperazine

SMILES

Cc1c(C(N(CC2)CCN2c2ccccc2)=O)c(CN(Cc(cc2)ccc2F)CC2)c2o1

InChI

InChI=1S/C26H28FN3O2/c1-19-25(26(31)30-15-13-29(14-16-30)22-5-3-2-4-6-22)23-18-28(12-11-24(23)32-19)17-20-7-9-21(27)10-8-20/h2-10H,11-18H2,1H3

InChI Key

XJSPRJXQXGZSPD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28994985

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.53

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.757

Distribution Coefficient, logD

-0.582

Water Solubility, LogSw

-4.19

Polar Surface Area

31.769

Acid Dissociation Constant (pKa)

25.85

Base Dissociation Constant (pKb)

11.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

T829-1492 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T829-1492 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T829-1492?
Check Price and Availability of T829-1492, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T829-1492 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T829-1492
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T829-1492
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T829-1492 available by request