T835-1845 Screening compound: 3-{[3-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-phenylpyrrolidine-1-carboxamide

T835-1845 Screening compound: 3-{[3-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-phenylpyrrolidine-1-carboxamide
T835-1845 Screening compound: 3-{[3-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-phenylpyrrolidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T835-1845
3-{[3-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-phenylpyrrolidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T835-1845

Molecular Formula

C22H27N5O (C22 H27 N5 O)

Compound Name

3-{[3-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-phenylpyrrolidine-1-carboxamide

IUPAC name

3-{[3-(2-methylpropyl)-3H-imidazo[45-b]pyridin-2-yl]methyl}-N-phenylpyrrolidine-1-carboxamide

SMILES

CC(C)Cn1c(nccc2)c2nc1CC(CC1)CN1C(Nc1ccccc1)=O

InChI

InChI=1S/C22H27N5O/c1-16(2)14-27-20(25-19-9-6-11-23-21(19)27)13-17-10-12-26(15-17)22(28)24-18-7-4-3-5-8-18/h3-9,11,16-17H,10,12-15H2,1-2H3,(H,24,28)/t17-/m0/s1

InChI Key

DJKNXUFQSITBEP-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD28121582

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.976

Distribution Coefficient, logD

3.976

Water Solubility, LogSw

-4.02

Polar Surface Area

46.818

Acid Dissociation Constant (pKa)

14.03

Base Dissociation Constant (pKb)

3.35

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.90

T835-1845 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T835-1845 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T835-1845?
Check Price and Availability of T835-1845, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T835-1845 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T835-1845
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T835-1845
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T835-1845 available by request