T842-1546 Screening compound: N-(2,5-difluorophenyl)-3-[3-(propan-2-yl)-3H-imidazo[4,5-c]pyridin-2-yl]pyrrolidine-1-carboxamide

T842-1546 Screening compound: N-(2,5-difluorophenyl)-3-[3-(propan-2-yl)-3H-imidazo[4,5-c]pyridin-2-yl]pyrrolidine-1-carboxamide
T842-1546 Screening compound: N-(2,5-difluorophenyl)-3-[3-(propan-2-yl)-3H-imidazo[4,5-c]pyridin-2-yl]pyrrolidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T842-1546
N-(2,5-difluorophenyl)-3-[3-(propan-2-yl)-3H-imidazo[4,5-c]pyridin-2-yl]pyrrolidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T842-1546

Molecular Formula

C20H21F2N5O (C20 H21 F2 N5 O)

Compound Name

N-(2,5-difluorophenyl)-3-[3-(propan-2-yl)-3H-imidazo[4,5-c]pyridin-2-yl]pyrrolidine-1-carboxamide

IUPAC name

N-(25-difluorophenyl)-3-[3-(propan-2-yl)-3H-imidazo[45-c]pyridin-2-yl]pyrrolidine-1-carboxamide

SMILES

CC(C)n1c(cncc2)c2nc1C(CC1)CN1C(Nc(cc(cc1)F)c1F)=O

InChI

InChI=1S/C20H21F2N5O/c1-12(2)27-18-10-23-7-5-16(18)24-19(27)13-6-8-26(11-13)20(28)25-17-9-14(21)3-4-15(17)22/h3-5,7,9-10,12-13H,6,8,11H2,1-2H3,(H,25,28)

InChI Key

ZBSMARHZNZRGGT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28121763

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.889

Distribution Coefficient, logD

3.888

Water Solubility, LogSw

-3.61

Polar Surface Area

45.831

Acid Dissociation Constant (pKa)

10.17

Base Dissociation Constant (pKb)

3.94

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

35.00

T842-1546 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

Nucleic Acid Ligands (8311 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Agro:
  • Agro

References: we are preparing a list of scientific research reports with T842-1546 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T842-1546?
Check Price and Availability of T842-1546, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T842-1546 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T842-1546
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T842-1546
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T842-1546 available by request