T865-3325 Screening compound: N,N-dimethyl-4-(pyridin-3-yl)-1-(pyridine-4-carbonyl)pyrrolidine-3-carboxamide

T865-3325 Screening compound: N,N-dimethyl-4-(pyridin-3-yl)-1-(pyridine-4-carbonyl)pyrrolidine-3-carboxamide
T865-3325 Screening compound: N,N-dimethyl-4-(pyridin-3-yl)-1-(pyridine-4-carbonyl)pyrrolidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T865-3325
N,N-dimethyl-4-(pyridin-3-yl)-1-(pyridine-4-carbonyl)pyrrolidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T865-3325

Molecular Formula

C18H20N4O2 (C18 H20 N4 O2)

Compound Name

N,N-dimethyl-4-(pyridin-3-yl)-1-(pyridine-4-carbonyl)pyrrolidine-3-carboxamide

IUPAC name

(3S4R)-NN-dimethyl-4-(pyridin-3-yl)-1-(pyridine-4-carbonyl)pyrrolidine-3-carboxamide

SMILES

CN(C)C([C@@H](CN(C1)C(c2ccncc2)=O)[C@H]1c1cnccc1)=O

InChI

InChI=1S/C18H20N4O2/c1-21(2)18(24)16-12-22(17(23)13-5-8-19-9-6-13)11-15(16)14-4-3-7-20-10-14/h3-10,15-16H,11-12H2,1-2H3/t15-,16+/m0/s1

InChI Key

RMEGDWTWHZNWOS-JKSUJKDBSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

324.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

-0.413

Distribution Coefficient, logD

-0.416

Water Solubility, LogSw

-0.87

Polar Surface Area

51.795

Acid Dissociation Constant (pKa)

20.09

Base Dissociation Constant (pKb)

5.14

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

33.30

T865-3325 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

CNS Targets (44014 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Ion Channels Focused Library (26372 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
  • Nervous system
  • Nervous system
  • Cardiovascular
  • Cancer
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with T865-3325 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T865-3325?
Check Price and Availability of T865-3325, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T865-3325 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T865-3325
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T865-3325
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T865-3325 available by request