T990-4908 Screening compound: 3-[4-(2-cyclohexylacetyl)piperazin-1-yl]-1-(2-phenylethyl)pyrrolidin-2-one

T990-4908 Screening compound: 3-[4-(2-cyclohexylacetyl)piperazin-1-yl]-1-(2-phenylethyl)pyrrolidin-2-one
T990-4908 Screening compound: 3-[4-(2-cyclohexylacetyl)piperazin-1-yl]-1-(2-phenylethyl)pyrrolidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T990-4908
3-[4-(2-cyclohexylacetyl)piperazin-1-yl]-1-(2-phenylethyl)pyrrolidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T990-4908

Molecular Formula

C24H35N3O2 (C24 H35 N3 O2)

Compound Name

3-[4-(2-cyclohexylacetyl)piperazin-1-yl]-1-(2-phenylethyl)pyrrolidin-2-one

IUPAC name

3-[4-(2-cyclohexylacetyl)piperazin-1-yl]-1-(2-phenylethyl)pyrrolidin-2-one

SMILES

O=C(CC1CCCCC1)N(CC1)CCN1C(CCN1CCc2ccccc2)C1=O

InChI

InChI=1S/C24H35N3O2/c28-23(19-21-9-5-2-6-10-21)26-17-15-25(16-18-26)22-12-14-27(24(22)29)13-11-20-7-3-1-4-8-20/h1,3-4,7-8,21-22H,2,5-6,9-19H2/t22-/m0/s1

InChI Key

FEVIHSKFBCLTDH-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD28993450

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.223

Distribution Coefficient, logD

3.223

Water Solubility, LogSw

-3.30

Polar Surface Area

35.881

Acid Dissociation Constant (pKa)

14.92

Base Dissociation Constant (pKb)

4.59

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

66.70

T990-4908 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

GPCR Targeted Library (31838 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Targets:
  • GPCR
Structure:
  • Mimetics
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with T990-4908 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T990-4908?
Check Price and Availability of T990-4908, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T990-4908 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T990-4908
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T990-4908
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T990-4908 available by request