T993-1133 Screening compound: N-(2,4-difluorophenyl)-N'-({5-methyl-4-[(4-methylpiperidino)carbonyl]-1,3-oxazol-2-yl}methyl)urea

T993-1133 Screening compound: N-(2,4-difluorophenyl)-N'-({5-methyl-4-[(4-methylpiperidino)carbonyl]-1,3-oxazol-2-yl}methyl)urea
T993-1133 Screening compound: N-(2,4-difluorophenyl)-N'-({5-methyl-4-[(4-methylpiperidino)carbonyl]-1,3-oxazol-2-yl}methyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound T993-1133
N-(2,4-difluorophenyl)-N'-({5-methyl-4-[(4-methylpiperidino)carbonyl]-1,3-oxazol-2-yl}methyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T993-1133

Molecular Formula

C19H22F2N4O3 (C19 H22 F2 N4 O3)

Compound Name

N-(2,4-difluorophenyl)-N'-({5-methyl-4-[(4-methylpiperidino)carbonyl]-1,3-oxazol-2-yl}methyl)urea

IUPAC name

1-(24-difluorophenyl)-3-{[5-methyl-4-(4-methylpiperidine-1-carbonyl)-13-oxazol-2-yl]methyl}urea

SMILES

CC(CC1)CCN1C(c1c(C)oc(CNC(Nc(ccc(F)c2)c2F)=O)n1)=O

InChI

InChI=1S/C19H22F2N4O3/c1-11-5-7-25(8-6-11)18(26)17-12(2)28-16(24-17)10-22-19(27)23-15-4-3-13(20)9-14(15)21/h3-4,9,11H,5-8,10H2,1-2H3,(H2,22,23,27)

InChI Key

GIKIKUUROWVXGF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29029072

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.716

Distribution Coefficient, logD

2.716

Water Solubility, LogSw

-3.11

Polar Surface Area

67.378

Acid Dissociation Constant (pKa)

10.07

Base Dissociation Constant (pKb)

-1.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

T993-1133 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with T993-1133 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T993-1133?
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What is the minimum amount of T993-1133 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T993-1133
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T993-1133
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T993-1133 available by request