V002-1380 Screening compound: 1-cyclopropanecarbonyl-4-(2,3-dimethoxyphenyl)-N-[(4-fluorophenyl)methyl]pyrrolidine-3-carboxamide

V002-1380 Screening compound: 1-cyclopropanecarbonyl-4-(2,3-dimethoxyphenyl)-N-[(4-fluorophenyl)methyl]pyrrolidine-3-carboxamide
V002-1380 Screening compound: 1-cyclopropanecarbonyl-4-(2,3-dimethoxyphenyl)-N-[(4-fluorophenyl)methyl]pyrrolidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V002-1380
1-cyclopropanecarbonyl-4-(2,3-dimethoxyphenyl)-N-[(4-fluorophenyl)methyl]pyrrolidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V002-1380

Molecular Formula

C24H27FN2O4 (C24 H27 FN2 O4)

Compound Name

1-cyclopropanecarbonyl-4-(2,3-dimethoxyphenyl)-N-[(4-fluorophenyl)methyl]pyrrolidine-3-carboxamide

IUPAC name

1-cyclopropanecarbonyl-4-(23-dimethoxyphenyl)-N-[(4-fluorophenyl)methyl]pyrrolidine-3-carboxamide

SMILES

COc1cccc(C(CN(C2)C(C3CC3)=O)C2C(NCc(cc2)ccc2F)=O)c1OC

InChI

InChI=1S/C24H27FN2O4/c1-30-21-5-3-4-18(22(21)31-2)19-13-27(24(29)16-8-9-16)14-20(19)23(28)26-12-15-6-10-17(25)11-7-15/h3-7,10-11,16,19-20H,8-9,12-14H2,1-2H3,(H,26,28)

InChI Key

OVXWSRIEFVDIET-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14261679

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.755

Distribution Coefficient, logD

2.755

Water Solubility, LogSw

-3.07

Polar Surface Area

57.132

Acid Dissociation Constant (pKa)

11.47

Base Dissociation Constant (pKb)

1.46

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

41.70

V002-1380 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V002-1380 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V002-1380?
Check Price and Availability of V002-1380, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V002-1380 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V002-1380
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V002-1380
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V002-1380 available by request