V002-8748 Screening compound: 4-(4-fluorobenzoyl)-8-(3-methylbenzoyl)-3-(morpholine-4-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane

V002-8748 Screening compound: 4-(4-fluorobenzoyl)-8-(3-methylbenzoyl)-3-(morpholine-4-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane
V002-8748 Screening compound: 4-(4-fluorobenzoyl)-8-(3-methylbenzoyl)-3-(morpholine-4-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound V002-8748
4-(4-fluorobenzoyl)-8-(3-methylbenzoyl)-3-(morpholine-4-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V002-8748

Molecular Formula

C27H30FN3O5 (C27 H30 FN3 O5)

Compound Name

4-(4-fluorobenzoyl)-8-(3-methylbenzoyl)-3-(morpholine-4-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane

IUPAC name

4-(4-fluorobenzoyl)-8-(3-methylbenzoyl)-3-(morpholine-4-carbonyl)-1-oxa-48-diazaspiro[4.5]decane

SMILES

Cc1cccc(C(N(CC2)CCC22OCC(C(N3CCOCC3)=O)N2C(c(cc2)ccc2F)=O)=O)c1

InChI

InChI=1S/C27H30FN3O5/c1-19-3-2-4-21(17-19)24(32)29-11-9-27(10-12-29)31(25(33)20-5-7-22(28)8-6-20)23(18-36-27)26(34)30-13-15-35-16-14-30/h2-8,17,23H,9-16,18H2,1H3/t23-/m0/s1

InChI Key

CLELOGJBTWMWDP-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD19813821

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.55

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.630

Distribution Coefficient, logD

1.630

Water Solubility, LogSw

-1.88

Polar Surface Area

64.139

Acid Dissociation Constant (pKa)

20.29

Base Dissociation Constant (pKb)

-1.36

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.40

V002-8748 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V002-8748 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V002-8748?
Check Price and Availability of V002-8748, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V002-8748 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V002-8748
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V002-8748
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V002-8748 available by request