V003-2525 Screening compound: 2,4-dichloro-N-(3-{4-oxo-3-[4-(trifluoromethyl)phenyl]-1,3-thiazolidin-2-yl}phenyl)benzamide

V003-2525 Screening compound: 2,4-dichloro-N-(3-{4-oxo-3-[4-(trifluoromethyl)phenyl]-1,3-thiazolidin-2-yl}phenyl)benzamide
V003-2525 Screening compound: 2,4-dichloro-N-(3-{4-oxo-3-[4-(trifluoromethyl)phenyl]-1,3-thiazolidin-2-yl}phenyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V003-2525
2,4-dichloro-N-(3-{4-oxo-3-[4-(trifluoromethyl)phenyl]-1,3-thiazolidin-2-yl}phenyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V003-2525

Molecular Formula

C23H15Cl2F3N2O2S (C23 H15 Cl2 F3 N2 O2 S)

Compound Name

2,4-dichloro-N-(3-{4-oxo-3-[4-(trifluoromethyl)phenyl]-1,3-thiazolidin-2-yl}phenyl)benzamide

IUPAC name

24-dichloro-N-(3-{4-oxo-3-[4-(trifluoromethyl)phenyl]-13-thiazolidin-2-yl}phenyl)benzamide

SMILES

O=C(c(ccc(Cl)c1)c1Cl)Nc1cc(C(N2c3ccc(C(F)(F)F)cc3)SCC2=O)ccc1

InChI

InChI=1S/C23H15Cl2F3N2O2S/c24-15-6-9-18(19(25)11-15)21(32)29-16-3-1-2-13(10-16)22-30(20(31)12-33-22)17-7-4-14(5-8-17)23(26,27)28/h1-11,22H,12H2,(H,29,32)/t22-/m0/s1

InChI Key

CUCBMONTVKUKPF-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD19860209

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

511.35

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.228

Distribution Coefficient, logD

6.216

Water Solubility, LogSw

-6.40

Polar Surface Area

39.224

Acid Dissociation Constant (pKa)

8.98

Base Dissociation Constant (pKb)

-1.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.00

V003-2525 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V003-2525 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V003-2525?
Check Price and Availability of V003-2525, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V003-2525 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V003-2525
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V003-2525
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V003-2525 available by request