V003-7250 Screening compound: N-{4-[3-(4-ethylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-4-methyl-3-nitrobenzamide

V003-7250 Screening compound: N-{4-[3-(4-ethylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-4-methyl-3-nitrobenzamide
V003-7250 Screening compound: N-{4-[3-(4-ethylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-4-methyl-3-nitrobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V003-7250
N-{4-[3-(4-ethylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-4-methyl-3-nitrobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V003-7250

Molecular Formula

C25H23N3O4S (C25 H23 N3 O4 S)

Compound Name

N-{4-[3-(4-ethylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-4-methyl-3-nitrobenzamide

IUPAC name

N-{4-[3-(4-ethylphenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}-4-methyl-3-nitrobenzamide

SMILES

CCc(cc1)ccc1N(C(c(cc1)ccc1NC(c1cc([N+]([O-])=O)c(C)cc1)=O)SC1)C1=O

InChI

InChI=1S/C25H23N3O4S/c1-3-17-5-12-21(13-6-17)27-23(29)15-33-25(27)18-8-10-20(11-9-18)26-24(30)19-7-4-16(2)22(14-19)28(31)32/h4-14,25H,3,15H2,1-2H3,(H,26,30)/t25-/m0/s1

InChI Key

ZCBGJHOAYQDQBI-VWLOTQADSA-N

MDL Number (MFCD)

MFCD19856836

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.367

Distribution Coefficient, logD

5.365

Water Solubility, LogSw

-5.39

Polar Surface Area

72.305

Acid Dissociation Constant (pKa)

9.85

Base Dissociation Constant (pKb)

-2.94

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

V003-7250 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V003-7250 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V003-7250?
Check Price and Availability of V003-7250, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V003-7250 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V003-7250
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V003-7250
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V003-7250 available by request