V004-1919 Screening compound: 8-(2,4-difluorobenzoyl)-4-(4-fluorobenzoyl)-N-(2-methoxyethyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxamide

V004-1919 Screening compound: 8-(2,4-difluorobenzoyl)-4-(4-fluorobenzoyl)-N-(2-methoxyethyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxamide
V004-1919 Screening compound: 8-(2,4-difluorobenzoyl)-4-(4-fluorobenzoyl)-N-(2-methoxyethyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V004-1919
8-(2,4-difluorobenzoyl)-4-(4-fluorobenzoyl)-N-(2-methoxyethyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V004-1919

Molecular Formula

C25H26F3N3O5 (C25 H26 F3 N3 O5)

Compound Name

8-(2,4-difluorobenzoyl)-4-(4-fluorobenzoyl)-N-(2-methoxyethyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxamide

IUPAC name

8-(24-difluorobenzoyl)-4-(4-fluorobenzoyl)-N-(2-methoxyethyl)-1-oxa-48-diazaspiro[4.5]decane-3-carboxamide

SMILES

COCCNC(C(COC1(CC2)CCN2C(c(ccc(F)c2)c2F)=O)N1C(c(cc1)ccc1F)=O)=O

InChI

InChI=1S/C25H26F3N3O5/c1-35-13-10-29-22(32)21-15-36-25(31(21)23(33)16-2-4-17(26)5-3-16)8-11-30(12-9-25)24(34)19-7-6-18(27)14-20(19)28/h2-7,14,21H,8-13,15H2,1H3,(H,29,32)/t21-/m1/s1

InChI Key

ZWLQJHWVULQIOR-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD19806439

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

505.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.954

Distribution Coefficient, logD

1.954

Water Solubility, LogSw

-2.76

Polar Surface Area

72.451

Acid Dissociation Constant (pKa)

14.46

Base Dissociation Constant (pKb)

-0.05

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.00

V004-1919 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Antiviral HBV Library (10007 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Anti-HIV1 Library (19540 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V004-1919 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V004-1919?
Check Price and Availability of V004-1919, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V004-1919 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V004-1919
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V004-1919
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V004-1919 available by request