V004-6220 Screening compound: 1-{2-cyclopropyl-5,6-dimethylthieno[2,3-d]pyrimidin-4-yl}-4-(4-fluorobenzoyl)piperazine

V004-6220 Screening compound: 1-{2-cyclopropyl-5,6-dimethylthieno[2,3-d]pyrimidin-4-yl}-4-(4-fluorobenzoyl)piperazine
V004-6220 Screening compound: 1-{2-cyclopropyl-5,6-dimethylthieno[2,3-d]pyrimidin-4-yl}-4-(4-fluorobenzoyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound V004-6220
1-{2-cyclopropyl-5,6-dimethylthieno[2,3-d]pyrimidin-4-yl}-4-(4-fluorobenzoyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V004-6220

Molecular Formula

C22H23FN4OS (C22 H23 FN4 OS)

Compound Name

1-{2-cyclopropyl-5,6-dimethylthieno[2,3-d]pyrimidin-4-yl}-4-(4-fluorobenzoyl)piperazine

IUPAC name

1-{2-cyclopropyl-56-dimethylthieno[23-d]pyrimidin-4-yl}-4-(4-fluorobenzoyl)piperazine

SMILES

Cc1c(C)sc2nc(C3CC3)nc(N(CC3)CCN3C(c(cc3)ccc3F)=O)c12

InChI

InChI=1S/C22H23FN4OS/c1-13-14(2)29-21-18(13)20(24-19(25-21)15-3-4-15)26-9-11-27(12-10-26)22(28)16-5-7-17(23)8-6-16/h5-8,15H,3-4,9-12H2,1-2H3

InChI Key

HMYWMLYNCDJDNV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03432042

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

410.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.895

Distribution Coefficient, logD

2.573

Water Solubility, LogSw

-4.82

Polar Surface Area

40.008

Acid Dissociation Constant (pKa)

22.46

Base Dissociation Constant (pKb)

9.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

V004-6220 in Drug Discovery

Included in Screening Libraries

CNS targets activity set (6557 compounds)

GPCR Targeted Library (31838 compounds)

Nucleic Acid Ligands (8311 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V004-6220 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V004-6220?
Check Price and Availability of V004-6220, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V004-6220 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V004-6220
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V004-6220
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V004-6220 available by request