V005-4474 Screening compound: N-benzyl-N-{2-[6-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]ethyl}quinoline-8-sulfonamide

V005-4474 Screening compound: N-benzyl-N-{2-[6-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]ethyl}quinoline-8-sulfonamide
V005-4474 Screening compound: N-benzyl-N-{2-[6-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]ethyl}quinoline-8-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V005-4474
N-benzyl-N-{2-[6-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]ethyl}quinoline-8-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V005-4474

Molecular Formula

C29H23FN4O2S2 (C29 H23 FN4 O2 S2)

Compound Name

N-benzyl-N-{2-[6-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]ethyl}quinoline-8-sulfonamide

IUPAC name

N-benzyl-N-{2-[6-(4-fluorophenyl)imidazo[21-b][13]thiazol-3-yl]ethyl}quinoline-8-sulfonamide

SMILES

O=S(c1cccc2cccnc12)(N(CCc1csc2nc(-c(cc3)ccc3F)cn12)Cc1ccccc1)=O

InChI

InChI=1S/C29H23FN4O2S2/c30-24-13-11-22(12-14-24)26-19-34-25(20-37-29(34)32-26)15-17-33(18-21-6-2-1-3-7-21)38(35,36)27-10-4-8-23-9-5-16-31-28(23)27/h1-14,16,19-20H,15,17-18H2

InChI Key

LRRPXZAXHBATLM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19774970

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

542.66

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.867

Distribution Coefficient, logD

5.867

Water Solubility, LogSw

-6.49

Polar Surface Area

49.792

Acid Dissociation Constant (pKa)

26.01

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.34

V005-4474 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V005-4474 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V005-4474?
Check Price and Availability of V005-4474, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V005-4474 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V005-4474
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V005-4474
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V005-4474 available by request