V005-8125 Screening compound: N~1~-(2-{[2-(2-furyl)-6-methyl-4-quinazolinyl]amino}ethyl)-1-cyclobutanecarboxamide

V005-8125 Screening compound: N~1~-(2-{[2-(2-furyl)-6-methyl-4-quinazolinyl]amino}ethyl)-1-cyclobutanecarboxamide
V005-8125 Screening compound: N~1~-(2-{[2-(2-furyl)-6-methyl-4-quinazolinyl]amino}ethyl)-1-cyclobutanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V005-8125
N~1~-(2-{[2-(2-furyl)-6-methyl-4-quinazolinyl]amino}ethyl)-1-cyclobutanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V005-8125

Molecular Formula

C20H22N4O2 (C20 H22 N4 O2)

Compound Name

N~1~-(2-{[2-(2-furyl)-6-methyl-4-quinazolinyl]amino}ethyl)-1-cyclobutanecarboxamide

IUPAC name

n/a

SMILES

Cc(cc12)ccc2nc(-c2ccco2)nc1NCCNC(C1CCC1)=O

InChI

InChI=1S/C20H22N4O2/c1-13-7-8-16-15(12-13)18(24-19(23-16)17-6-3-11-26-17)21-9-10-22-20(25)14-4-2-5-14/h3,6-8,11-12,14H,2,4-5,9-10H2,1H3,(H,22,25)(H,21,23,24)

InChI Key

NOFAPXPBEHFODS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD20494252

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.909

Distribution Coefficient, logD

2.892

Water Solubility, LogSw

-3.02

Polar Surface Area

62.597

Acid Dissociation Constant (pKa)

14.53

Base Dissociation Constant (pKb)

5.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

V005-8125 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with V005-8125 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V005-8125?
Check Price and Availability of V005-8125, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V005-8125 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V005-8125
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V005-8125
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V005-8125 available by request