V007-1443 Screening compound: 3-(1H-indol-3-yl)-1-(4-methylpiperidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-1-one

V007-1443 Screening compound: 3-(1H-indol-3-yl)-1-(4-methylpiperidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-1-one
V007-1443 Screening compound: 3-(1H-indol-3-yl)-1-(4-methylpiperidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V007-1443
3-(1H-indol-3-yl)-1-(4-methylpiperidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V007-1443

Molecular Formula

C24H25F3N2O (C24 H25 F3 N2 O)

Compound Name

3-(1H-indol-3-yl)-1-(4-methylpiperidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-1-one

IUPAC name

3-(1H-indol-3-yl)-1-(4-methylpiperidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-1-one

SMILES

CC(CC1)CCN1C(CC(c1c[nH]c2c1cccc2)c1cccc(C(F)(F)F)c1)=O

InChI

InChI=1S/C24H25F3N2O/c1-16-9-11-29(12-10-16)23(30)14-20(17-5-4-6-18(13-17)24(25,26)27)21-15-28-22-8-3-2-7-19(21)22/h2-8,13,15-16,20,28H,9-12,14H2,1H3/t20-/m1/s1

InChI Key

LLWRULCFGVJSFZ-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD19850828

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.47

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.538

Distribution Coefficient, logD

5.538

Water Solubility, LogSw

-5.91

Polar Surface Area

25.959

Acid Dissociation Constant (pKa)

17.49

Base Dissociation Constant (pKb)

-0.22

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

V007-1443 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V007-1443 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V007-1443?
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What is the minimum amount of V007-1443 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V007-1443
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V007-1443
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V007-1443 available by request