V008-5174 Screening compound: 1-[(3,4-difluorophenyl)methyl]-5-methoxy-N-[(3-methylphenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

V008-5174 Screening compound: 1-[(3,4-difluorophenyl)methyl]-5-methoxy-N-[(3-methylphenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide
V008-5174 Screening compound: 1-[(3,4-difluorophenyl)methyl]-5-methoxy-N-[(3-methylphenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V008-5174
1-[(3,4-difluorophenyl)methyl]-5-methoxy-N-[(3-methylphenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V008-5174

Molecular Formula

C27H25F2N3O3S (C27 H25 F2 N3 O3 S)

Compound Name

1-[(3,4-difluorophenyl)methyl]-5-methoxy-N-[(3-methylphenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

IUPAC name

1-[(34-difluorophenyl)methyl]-5-methoxy-N-[(3-methylphenyl)methyl]-2-oxo-12-dihydrospiro[indole-32'-[13]thiazolidine]-3'-carboxamide

SMILES

Cc1cccc(CNC(N2C(c(cc(cc3)OC)c3N3Cc(cc4)cc(F)c4F)(C3=O)SCC2)=O)c1

InChI

InChI=1S/C27H25F2N3O3S/c1-17-4-3-5-18(12-17)15-30-26(34)32-10-11-36-27(32)21-14-20(35-2)7-9-24(21)31(25(27)33)16-19-6-8-22(28)23(29)13-19/h3-9,12-14H,10-11,15-16H2,1-2H3,(H,30,34)/t27-/m0/s1

InChI Key

HQNMPDGBWJQXAF-MHZLTWQESA-N

MDL Number (MFCD)

MFCD19871750

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

509.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.501

Distribution Coefficient, logD

5.501

Water Solubility, LogSw

-5.36

Polar Surface Area

49.266

Acid Dissociation Constant (pKa)

15.00

Base Dissociation Constant (pKb)

-2.37

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.90

V008-5174 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

KRAS-Targeted Library (16000 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V008-5174 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V008-5174?
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What is the minimum amount of V008-5174 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V008-5174
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V008-5174
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V008-5174 available by request