V008-8658 Screening compound: 4-tert-butyl-N-{3-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}benzamide

V008-8658 Screening compound: 4-tert-butyl-N-{3-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}benzamide
V008-8658 Screening compound: 4-tert-butyl-N-{3-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V008-8658
4-tert-butyl-N-{3-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V008-8658

Molecular Formula

C27H27FN2O2S (C27 H27 FN2 O2 S)

Compound Name

4-tert-butyl-N-{3-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}benzamide

IUPAC name

4-tert-butyl-N-{3-[3-(3-fluoro-4-methylphenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}benzamide

SMILES

CC(C)(C)c(cc1)ccc1C(Nc1cccc(C(N2c3cc(F)c(C)cc3)SCC2=O)c1)=O

InChI

InChI=1S/C27H27FN2O2S/c1-17-8-13-22(15-23(17)28)30-24(31)16-33-26(30)19-6-5-7-21(14-19)29-25(32)18-9-11-20(12-10-18)27(2,3)4/h5-15,26H,16H2,1-4H3,(H,29,32)/t26-/m0/s1

InChI Key

AMAPICVJRUASNW-SANMLTNESA-N

MDL Number (MFCD)

MFCD19861729

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.59

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.650

Distribution Coefficient, logD

6.650

Water Solubility, LogSw

-5.64

Polar Surface Area

39.224

Acid Dissociation Constant (pKa)

10.76

Base Dissociation Constant (pKb)

-1.13

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.90

V008-8658 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V008-8658 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V008-8658?
Check Price and Availability of V008-8658, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V008-8658 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V008-8658
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V008-8658
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V008-8658 available by request