V010-0649 Screening compound: 1-[1-(2-fluorophenyl)-1,2,3,4-tetrahydroisoquinolin-2-yl]-2,2-diphenylethan-1-one

V010-0649 Screening compound: 1-[1-(2-fluorophenyl)-1,2,3,4-tetrahydroisoquinolin-2-yl]-2,2-diphenylethan-1-one
V010-0649 Screening compound: 1-[1-(2-fluorophenyl)-1,2,3,4-tetrahydroisoquinolin-2-yl]-2,2-diphenylethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V010-0649
1-[1-(2-fluorophenyl)-1,2,3,4-tetrahydroisoquinolin-2-yl]-2,2-diphenylethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V010-0649

Molecular Formula

C29H24FNO (C29 H24 FNO)

Compound Name

1-[1-(2-fluorophenyl)-1,2,3,4-tetrahydroisoquinolin-2-yl]-2,2-diphenylethan-1-one

IUPAC name

1-[1-(2-fluorophenyl)-1234-tetrahydroisoquinolin-2-yl]-22-diphenylethan-1-one

SMILES

O=C(C(c1ccccc1)c1ccccc1)N(CCc1c2cccc1)C2c(cccc1)c1F

InChI

InChI=1S/C29H24FNO/c30-26-18-10-9-17-25(26)28-24-16-8-7-11-21(24)19-20-31(28)29(32)27(22-12-3-1-4-13-22)23-14-5-2-6-15-23/h1-18,27-28H,19-20H2/t28-/m0/s1

InChI Key

ITOYDCQVRMYPIG-NDEPHWFRSA-N

MDL Number (MFCD)

MFCD19957714

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.51

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

6.861

Distribution Coefficient, logD

6.861

Water Solubility, LogSw

-6.14

Polar Surface Area

15.590

Acid Dissociation Constant (pKa)

15.03

Base Dissociation Constant (pKb)

-4.82

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.80

V010-0649 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V010-0649 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V010-0649?
Check Price and Availability of V010-0649, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V010-0649 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V010-0649
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V010-0649
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V010-0649 available by request