V011-3776 Screening compound: N-{4-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}heptanamide

V011-3776 Screening compound: N-{4-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}heptanamide
V011-3776 Screening compound: N-{4-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}heptanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V011-3776
N-{4-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}heptanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V011-3776

Molecular Formula

C23H27FN2O2S (C23 H27 FN2 O2 S)

Compound Name

N-{4-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}heptanamide

IUPAC name

N-{4-[3-(3-fluoro-4-methylphenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}heptanamide

SMILES

CCCCCCC(Nc1ccc(C(N2c3cc(F)c(C)cc3)SCC2=O)cc1)=O

InChI

InChI=1S/C23H27FN2O2S/c1-3-4-5-6-7-21(27)25-18-11-9-17(10-12-18)23-26(22(28)15-29-23)19-13-8-16(2)20(24)14-19/h8-14,23H,3-7,15H2,1-2H3,(H,25,27)/t23-/m0/s1

InChI Key

RYZYDZNMFRBJGQ-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD19861697

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.503

Distribution Coefficient, logD

5.503

Water Solubility, LogSw

-5.19

Polar Surface Area

39.282

Acid Dissociation Constant (pKa)

12.40

Base Dissociation Constant (pKb)

1.98

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

39.10

V011-3776 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V011-3776 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V011-3776?
Check Price and Availability of V011-3776, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V011-3776 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V011-3776
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V011-3776
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V011-3776 available by request