V011-4609 Screening compound: 3-[1-(4-chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1-(2-fluorophenyl)-4-(4-methylpiperazin-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

V011-4609 Screening compound: 3-[1-(4-chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1-(2-fluorophenyl)-4-(4-methylpiperazin-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
V011-4609 Screening compound: 3-[1-(4-chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1-(2-fluorophenyl)-4-(4-methylpiperazin-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound V011-4609
3-[1-(4-chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1-(2-fluorophenyl)-4-(4-methylpiperazin-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V011-4609

Molecular Formula

C25H23ClFN5O3 (C25 H23 ClFN5 O3)

Compound Name

3-[1-(4-chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1-(2-fluorophenyl)-4-(4-methylpiperazin-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

IUPAC name

3-[1-(4-chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1-(2-fluorophenyl)-4-(4-methylpiperazin-1-yl)-25-dihydro-1H-pyrrole-25-dione

SMILES

Cc(c(C(C(N(C1=O)c(cccc2)c2F)=O)=C1N1CCN(C)CC1)c1O)nn1-c(cc1)ccc1Cl

InChI

InChI=1S/C25H23ClFN5O3/c1-15-20(24(34)32(28-15)17-9-7-16(26)8-10-17)21-22(30-13-11-29(2)12-14-30)25(35)31(23(21)33)19-6-4-3-5-18(19)27/h3-10,34H,11-14H2,1-2H3

InChI Key

MGDDHPWJKSPHDE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19798436

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

495.94

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.390

Distribution Coefficient, logD

0.361

Water Solubility, LogSw

-2.82

Polar Surface Area

65.276

Acid Dissociation Constant (pKa)

5.37

Base Dissociation Constant (pKb)

6.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

V011-4609 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Nucleoside Mimetics Library (2197 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Cancer
  • Immune system
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with V011-4609 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V011-4609?
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What is the minimum amount of V011-4609 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V011-4609
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V011-4609
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V011-4609 available by request