V011-6154 Screening compound: N-(6-{4-[4-(difluoromethoxy)benzoyl]piperazin-1-yl}pyridin-3-yl)-4-methylbenzamide

V011-6154 Screening compound: N-(6-{4-[4-(difluoromethoxy)benzoyl]piperazin-1-yl}pyridin-3-yl)-4-methylbenzamide
V011-6154 Screening compound: N-(6-{4-[4-(difluoromethoxy)benzoyl]piperazin-1-yl}pyridin-3-yl)-4-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V011-6154
N-(6-{4-[4-(difluoromethoxy)benzoyl]piperazin-1-yl}pyridin-3-yl)-4-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V011-6154

Molecular Formula

C25H24F2N4O3 (C25 H24 F2 N4 O3)

Compound Name

N-(6-{4-[4-(difluoromethoxy)benzoyl]piperazin-1-yl}pyridin-3-yl)-4-methylbenzamide

IUPAC name

N-(6-{4-[4-(difluoromethoxy)benzoyl]piperazin-1-yl}pyridin-3-yl)-4-methylbenzamide

SMILES

Cc(cc1)ccc1C(Nc(cc1)cnc1N(CC1)CCN1C(c(cc1)ccc1OC(F)F)=O)=O

InChI

InChI=1S/C25H24F2N4O3/c1-17-2-4-18(5-3-17)23(32)29-20-8-11-22(28-16-20)30-12-14-31(15-13-30)24(33)19-6-9-21(10-7-19)34-25(26)27/h2-11,16,25H,12-15H2,1H3,(H,29,32)

InChI Key

CMQITDZEUVPREU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19946186

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

466.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.180

Distribution Coefficient, logD

4.179

Water Solubility, LogSw

-4.01

Polar Surface Area

58.444

Acid Dissociation Constant (pKa)

10.52

Base Dissociation Constant (pKb)

4.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

V011-6154 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with V011-6154 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V011-6154?
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What is the minimum amount of V011-6154 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V011-6154
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V011-6154
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V011-6154 available by request