V011-8370 Screening compound: 2-ethyl-N-{3-[3-(3-ethylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}hexanamide

V011-8370 Screening compound: 2-ethyl-N-{3-[3-(3-ethylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}hexanamide
V011-8370 Screening compound: 2-ethyl-N-{3-[3-(3-ethylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}hexanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V011-8370
2-ethyl-N-{3-[3-(3-ethylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}hexanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V011-8370

Molecular Formula

C25H32N2O2S (C25 H32 N2 O2 S)

Compound Name

2-ethyl-N-{3-[3-(3-ethylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}hexanamide

IUPAC name

2-ethyl-N-{3-[3-(3-ethylphenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}hexanamide

SMILES

CCCCC(CC)C(Nc1cccc(C(N2c3cc(CC)ccc3)SCC2=O)c1)=O

InChI

InChI=1S/C25H32N2O2S/c1-4-7-11-19(6-3)24(29)26-21-13-9-12-20(16-21)25-27(23(28)17-30-25)22-14-8-10-18(5-2)15-22/h8-10,12-16,19,25H,4-7,11,17H2,1-3H3,(H,26,29)

InChI Key

SCBCLBODFXMVEE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19861849

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.61

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.145

Distribution Coefficient, logD

6.145

Water Solubility, LogSw

-5.35

Polar Surface Area

39.496

Acid Dissociation Constant (pKa)

11.72

Base Dissociation Constant (pKb)

2.77

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

44.00

V011-8370 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V011-8370 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V011-8370?
Check Price and Availability of V011-8370, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V011-8370 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V011-8370
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V011-8370
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V011-8370 available by request