V011-8371 Screening compound: N-[(4-chlorophenyl)methyl]-2-[N-cyclopropyl-1-(2-fluorophenyl)formamido]-N-[2-(1H-indol-3-yl)ethyl]acetamide

V011-8371 Screening compound: N-[(4-chlorophenyl)methyl]-2-[N-cyclopropyl-1-(2-fluorophenyl)formamido]-N-[2-(1H-indol-3-yl)ethyl]acetamide
V011-8371 Screening compound: N-[(4-chlorophenyl)methyl]-2-[N-cyclopropyl-1-(2-fluorophenyl)formamido]-N-[2-(1H-indol-3-yl)ethyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V011-8371
N-[(4-chlorophenyl)methyl]-2-[N-cyclopropyl-1-(2-fluorophenyl)formamido]-N-[2-(1H-indol-3-yl)ethyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V011-8371

Molecular Formula

C29H27ClFN3O2 (C29 H27 ClFN3 O2)

Compound Name

N-[(4-chlorophenyl)methyl]-2-[N-cyclopropyl-1-(2-fluorophenyl)formamido]-N-[2-(1H-indol-3-yl)ethyl]acetamide

IUPAC name

N-[(4-chlorophenyl)methyl]-2-[N-cyclopropyl-1-(2-fluorophenyl)formamido]-N-[2-(1H-indol-3-yl)ethyl]acetamide

SMILES

O=C(CN(C1CC1)C(c(cccc1)c1F)=O)N(CCc1c[nH]c2c1cccc2)Cc(cc1)ccc1Cl

InChI

InChI=1S/C29H27ClFN3O2/c30-22-11-9-20(10-12-22)18-33(16-15-21-17-32-27-8-4-2-5-24(21)27)28(35)19-34(23-13-14-23)29(36)25-6-1-3-7-26(25)31/h1-12,17,23,32H,13-16,18-19H2

InChI Key

AMELQUHFIJARMA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19773596

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

504

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.318

Distribution Coefficient, logD

5.318

Water Solubility, LogSw

-6.10

Polar Surface Area

41.286

Acid Dissociation Constant (pKa)

18.49

Base Dissociation Constant (pKb)

-0.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.10

V011-8371 in Drug Discovery

Included in Screening Libraries

Indole Derivatives (10091 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V011-8371 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V011-8371?
Check Price and Availability of V011-8371, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V011-8371 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V011-8371
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V011-8371
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V011-8371 available by request