V012-1151 Screening compound: N-[1-(2,5-dichlorophenyl)-3-phenyl-1H-pyrazol-5-yl]-2-(trifluoromethyl)benzamide

V012-1151 Screening compound: N-[1-(2,5-dichlorophenyl)-3-phenyl-1H-pyrazol-5-yl]-2-(trifluoromethyl)benzamide
V012-1151 Screening compound: N-[1-(2,5-dichlorophenyl)-3-phenyl-1H-pyrazol-5-yl]-2-(trifluoromethyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V012-1151
N-[1-(2,5-dichlorophenyl)-3-phenyl-1H-pyrazol-5-yl]-2-(trifluoromethyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V012-1151

Molecular Formula

C23H14Cl2F3N3O (C23 H14 Cl2 F3 N3 O)

Compound Name

N-[1-(2,5-dichlorophenyl)-3-phenyl-1H-pyrazol-5-yl]-2-(trifluoromethyl)benzamide

IUPAC name

N-[1-(25-dichlorophenyl)-3-phenyl-1H-pyrazol-5-yl]-2-(trifluoromethyl)benzamide

SMILES

O=C(c1c(C(F)(F)F)cccc1)Nc1cc(-c2ccccc2)nn1-c(cc(cc1)Cl)c1Cl

InChI

InChI=1S/C23H14Cl2F3N3O/c24-15-10-11-18(25)20(12-15)31-21(13-19(30-31)14-6-2-1-3-7-14)29-22(32)16-8-4-5-9-17(16)23(26,27)28/h1-13H,(H,29,32)

InChI Key

XKHCKCYXMYNGOL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19950081

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.28

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.660

Distribution Coefficient, logD

6.137

Water Solubility, LogSw

-6.45

Polar Surface Area

37.192

Acid Dissociation Constant (pKa)

7.03

Base Dissociation Constant (pKb)

-4.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.30

V012-1151 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V012-1151 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V012-1151?
Check Price and Availability of V012-1151, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V012-1151 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V012-1151
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V012-1151
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V012-1151 available by request