V012-2148 Screening compound: 4-methoxy-N-[3-(morpholin-4-yl)propyl]-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-5-carboxamide

V012-2148 Screening compound: 4-methoxy-N-[3-(morpholin-4-yl)propyl]-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-5-carboxamide
V012-2148 Screening compound: 4-methoxy-N-[3-(morpholin-4-yl)propyl]-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V012-2148
4-methoxy-N-[3-(morpholin-4-yl)propyl]-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V012-2148

Molecular Formula

C24H31F3N6O3 (C24 H31 F3 N6 O3)

Compound Name

4-methoxy-N-[3-(morpholin-4-yl)propyl]-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-5-carboxamide

IUPAC name

4-methoxy-N-[3-(morpholin-4-yl)propyl]-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-5-carboxamide

SMILES

COc(nc(N(CC1)CCN1c1cccc(C(F)(F)F)c1)nc1)c1C(NCCCN1CCOCC1)=O

InChI

InChI=1S/C24H31F3N6O3/c1-35-22-20(21(34)28-6-3-7-31-12-14-36-15-13-31)17-29-23(30-22)33-10-8-32(9-11-33)19-5-2-4-18(16-19)24(25,26)27/h2,4-5,16-17H,3,6-15H2,1H3,(H,28,34)

InChI Key

YSZNPDYDTANEIH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19893269

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

508.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.693

Distribution Coefficient, logD

2.304

Water Solubility, LogSw

-3.14

Polar Surface Area

69.418

Acid Dissociation Constant (pKa)

12.05

Base Dissociation Constant (pKb)

7.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.20

V012-2148 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Ion Channels
  • Kinases

References: we are preparing a list of scientific research reports with V012-2148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V012-2148?
Check Price and Availability of V012-2148, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V012-2148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V012-2148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V012-2148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V012-2148 available by request