V012-7346 Screening compound: 1-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}-2-(3-methoxyphenyl)ethan-1-one

V012-7346 Screening compound: 1-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}-2-(3-methoxyphenyl)ethan-1-one
V012-7346 Screening compound: 1-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}-2-(3-methoxyphenyl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V012-7346
1-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}-2-(3-methoxyphenyl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V012-7346

Molecular Formula

C26H27ClN2O2 (C26 H27 ClN2 O2)

Compound Name

1-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}-2-(3-methoxyphenyl)ethan-1-one

IUPAC name

1-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}-2-(3-methoxyphenyl)ethan-1-one

SMILES

COc1cccc(CC(N(CC2)CCN2C(c2ccccc2)c(cc2)ccc2Cl)=O)c1

InChI

InChI=1S/C26H27ClN2O2/c1-31-24-9-5-6-20(18-24)19-25(30)28-14-16-29(17-15-28)26(21-7-3-2-4-8-21)22-10-12-23(27)13-11-22/h2-13,18,26H,14-17,19H2,1H3/t26-/m0/s1

InChI Key

JPNCMUNFUMJBQK-SANMLTNESA-N

MDL Number (MFCD)

MFCD19962096

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

434.97

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.333

Distribution Coefficient, logD

5.332

Water Solubility, LogSw

-6.16

Polar Surface Area

26.464

Acid Dissociation Constant (pKa)

18.21

Base Dissociation Constant (pKb)

4.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.90

V012-7346 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
Targets:
  • Kinases
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with V012-7346 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V012-7346?
Check Price and Availability of V012-7346, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V012-7346 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V012-7346
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V012-7346
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V012-7346 available by request