V012-8216 Screening compound: 4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-N-(2,3-dihydro-1H-inden-1-yl)benzamide

V012-8216 Screening compound: 4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-N-(2,3-dihydro-1H-inden-1-yl)benzamide
V012-8216 Screening compound: 4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-N-(2,3-dihydro-1H-inden-1-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V012-8216
4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-N-(2,3-dihydro-1H-inden-1-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V012-8216

Molecular Formula

C25H20ClN3O (C25 H20 ClN3 O)

Compound Name

4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-N-(2,3-dihydro-1H-inden-1-yl)benzamide

IUPAC name

4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-N-(23-dihydro-1H-inden-1-yl)benzamide

SMILES

O=C(c(cc1)ccc1-c1cc(-c(cc2)ccc2Cl)n[nH]1)NC(CC1)c2c1cccc2

InChI

InChI=1S/C25H20ClN3O/c26-20-12-9-18(10-13-20)24-15-23(28-29-24)17-5-7-19(8-6-17)25(30)27-22-14-11-16-3-1-2-4-21(16)22/h1-10,12-13,15,22H,11,14H2,(H,27,30)(H,28,29)/t22-/m0/s1

InChI Key

RZHYDRNLDHXOBK-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD19953983

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

413.91

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.158

Distribution Coefficient, logD

6.158

Water Solubility, LogSw

-6.37

Polar Surface Area

47.080

Acid Dissociation Constant (pKa)

11.29

Base Dissociation Constant (pKb)

0.94

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.00

V012-8216 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V012-8216 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V012-8216?
Check Price and Availability of V012-8216, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V012-8216 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V012-8216
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V012-8216
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V012-8216 available by request