V012-8370 Screening compound: 4-(2-chlorophenyl)-N6-cyclopentyl-2-phenyl-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

V012-8370 Screening compound: 4-(2-chlorophenyl)-N6-cyclopentyl-2-phenyl-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine
V012-8370 Screening compound: 4-(2-chlorophenyl)-N6-cyclopentyl-2-phenyl-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound V012-8370
4-(2-chlorophenyl)-N6-cyclopentyl-2-phenyl-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V012-8370

Molecular Formula

C22H21ClN6 (C22 H21 ClN6)

Compound Name

4-(2-chlorophenyl)-N6-cyclopentyl-2-phenyl-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

IUPAC name

4-(2-chlorophenyl)-N6-cyclopentyl-2-phenyl-2H-pyrazolo[34-d]pyrimidine-36-diamine

SMILES

Nc1c2c(-c(cccc3)c3Cl)nc(NC3CCCC3)nc2nn1-c1ccccc1

InChI

InChI=1S/C22H21ClN6/c23-17-13-7-6-12-16(17)19-18-20(24)29(15-10-2-1-3-11-15)28-21(18)27-22(26-19)25-14-8-4-5-9-14/h1-3,6-7,10-14H,4-5,8-9,24H2,(H,25,27,28)

InChI Key

HONWVQBSKGUECC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14248398

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

404.9

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.196

Distribution Coefficient, logD

5.195

Water Solubility, LogSw

-5.67

Polar Surface Area

64.902

Acid Dissociation Constant (pKa)

16.87

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

V012-8370 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V012-8370 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V012-8370?
Check Price and Availability of V012-8370, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V012-8370 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V012-8370
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V012-8370
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V012-8370 available by request