V012-8473 Screening compound: N-[(4-chlorophenyl)methyl]-N-(3-methylphenyl)-3-(trifluoromethyl)benzene-1-sulfonamide

V012-8473 Screening compound: N-[(4-chlorophenyl)methyl]-N-(3-methylphenyl)-3-(trifluoromethyl)benzene-1-sulfonamide
V012-8473 Screening compound: N-[(4-chlorophenyl)methyl]-N-(3-methylphenyl)-3-(trifluoromethyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V012-8473
N-[(4-chlorophenyl)methyl]-N-(3-methylphenyl)-3-(trifluoromethyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V012-8473

Molecular Formula

C21H17ClF3NO2S (C21 H17 ClF3 NO2 S)

Compound Name

N-[(4-chlorophenyl)methyl]-N-(3-methylphenyl)-3-(trifluoromethyl)benzene-1-sulfonamide

IUPAC name

N-[(4-chlorophenyl)methyl]-N-(3-methylphenyl)-3-(trifluoromethyl)benzene-1-sulfonamide

SMILES

Cc1cccc(N(Cc(cc2)ccc2Cl)S(c2cc(C(F)(F)F)ccc2)(=O)=O)c1

InChI

InChI=1S/C21H17ClF3NO2S/c1-15-4-2-6-19(12-15)26(14-16-8-10-18(22)11-9-16)29(27,28)20-7-3-5-17(13-20)21(23,24)25/h2-13H,14H2,1H3

InChI Key

QAYGVLIENZWNAE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19877260

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.89

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.377

Distribution Coefficient, logD

6.377

Water Solubility, LogSw

-6.50

Polar Surface Area

31.792

Acid Dissociation Constant (pKa)

24.78

Base Dissociation Constant (pKb)

-13.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

V012-8473 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V012-8473 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V012-8473?
Check Price and Availability of V012-8473, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V012-8473 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V012-8473
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V012-8473
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V012-8473 available by request