V014-0557 Screening compound: ethyl 2-{[2-(3,4-difluorobenzamido)-1,3-thiazol-4-yl]formamido}acetate

V014-0557 Screening compound: ethyl 2-{[2-(3,4-difluorobenzamido)-1,3-thiazol-4-yl]formamido}acetate
V014-0557 Screening compound: ethyl 2-{[2-(3,4-difluorobenzamido)-1,3-thiazol-4-yl]formamido}acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-0557
ethyl 2-{[2-(3,4-difluorobenzamido)-1,3-thiazol-4-yl]formamido}acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-0557

Molecular Formula

C15H13F2N3O4S (C15 H13 F2 N3 O4 S)

Compound Name

ethyl 2-{[2-(3,4-difluorobenzamido)-1,3-thiazol-4-yl]formamido}acetate

IUPAC name

ethyl 2-{[2-(34-difluorobenzamido)-13-thiazol-4-yl]formamido}acetate

SMILES

CCOC(CNC(c1csc(NC(c(cc2)cc(F)c2F)=O)n1)=O)=O

InChI

InChI=1S/C15H13F2N3O4S/c1-2-24-12(21)6-18-14(23)11-7-25-15(19-11)20-13(22)8-3-4-9(16)10(17)5-8/h3-5,7H,2,6H2,1H3,(H,18,23)(H,19,20,22)

InChI Key

GQMHMZQWYJBYNT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19976124

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

369.35

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.789

Distribution Coefficient, logD

1.115

Water Solubility, LogSw

-3.40

Polar Surface Area

78.220

Acid Dissociation Constant (pKa)

5.73

Base Dissociation Constant (pKb)

-3.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

V014-0557 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V014-0557 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-0557?
Check Price and Availability of V014-0557, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V014-0557 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-0557
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-0557
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-0557 available by request