V014-0695 Screening compound: 3-cyclopentyl-N-(4-{4-oxo-3-[4-(trifluoromethyl)phenyl]-1,3-thiazolidin-2-yl}phenyl)propanamide

V014-0695 Screening compound: 3-cyclopentyl-N-(4-{4-oxo-3-[4-(trifluoromethyl)phenyl]-1,3-thiazolidin-2-yl}phenyl)propanamide
V014-0695 Screening compound: 3-cyclopentyl-N-(4-{4-oxo-3-[4-(trifluoromethyl)phenyl]-1,3-thiazolidin-2-yl}phenyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-0695
3-cyclopentyl-N-(4-{4-oxo-3-[4-(trifluoromethyl)phenyl]-1,3-thiazolidin-2-yl}phenyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-0695

Molecular Formula

C24H25F3N2O2S (C24 H25 F3 N2 O2 S)

Compound Name

3-cyclopentyl-N-(4-{4-oxo-3-[4-(trifluoromethyl)phenyl]-1,3-thiazolidin-2-yl}phenyl)propanamide

IUPAC name

3-cyclopentyl-N-(4-{4-oxo-3-[4-(trifluoromethyl)phenyl]-13-thiazolidin-2-yl}phenyl)propanamide

SMILES

O=C(CCC1CCCC1)Nc1ccc(C(N2c3ccc(C(F)(F)F)cc3)SCC2=O)cc1

InChI

InChI=1S/C24H25F3N2O2S/c25-24(26,27)18-8-12-20(13-9-18)29-22(31)15-32-23(29)17-6-10-19(11-7-17)28-21(30)14-5-16-3-1-2-4-16/h6-13,16,23H,1-5,14-15H2,(H,28,30)/t23-/m0/s1

InChI Key

SJTAADYIKRZVAG-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD19860183

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.436

Distribution Coefficient, logD

5.436

Water Solubility, LogSw

-5.85

Polar Surface Area

39.569

Acid Dissociation Constant (pKa)

12.40

Base Dissociation Constant (pKb)

1.54

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.70

V014-0695 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V014-0695 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-0695?
Check Price and Availability of V014-0695, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V014-0695 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-0695
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-0695
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-0695 available by request