V014-2132 Screening compound: 3-[1-(3-chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1-(2,4-dimethoxyphenyl)-4-(morpholin-4-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

V014-2132 Screening compound: 3-[1-(3-chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1-(2,4-dimethoxyphenyl)-4-(morpholin-4-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
V014-2132 Screening compound: 3-[1-(3-chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1-(2,4-dimethoxyphenyl)-4-(morpholin-4-yl)-2,5-dihydro-1H-pyrrole-2,5-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-2132
3-[1-(3-chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1-(2,4-dimethoxyphenyl)-4-(morpholin-4-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-2132

Molecular Formula

C26H25ClN4O6 (C26 H25 ClN4 O6)

Compound Name

3-[1-(3-chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1-(2,4-dimethoxyphenyl)-4-(morpholin-4-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

IUPAC name

3-[1-(3-chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1-(24-dimethoxyphenyl)-4-(morpholin-4-yl)-25-dihydro-1H-pyrrole-25-dione

SMILES

Cc(c(C(C(N(C1=O)c(ccc(OC)c2)c2OC)=O)=C1N1CCOCC1)c1O)nn1-c1cccc(Cl)c1

InChI

InChI=1S/C26H25ClN4O6/c1-15-21(25(33)31(28-15)17-6-4-5-16(27)13-17)22-23(29-9-11-37-12-10-29)26(34)30(24(22)32)19-8-7-18(35-2)14-20(19)36-3/h4-8,13-14,33H,9-12H2,1-3H3

InChI Key

XATWCPMIAMBCHS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19798249

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

524.96

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.488

Distribution Coefficient, logD

2.488

Water Solubility, LogSw

-2.97

Polar Surface Area

84.882

Acid Dissociation Constant (pKa)

5.29

Base Dissociation Constant (pKb)

7.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

V014-2132 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with V014-2132 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-2132?
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What is the minimum amount of V014-2132 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-2132
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-2132
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-2132 available by request