V014-4270 Screening compound: 2-(3-fluorobenzamido)-N-[3-(morpholin-4-yl)propyl]-1,3-thiazole-4-carboxamide

V014-4270 Screening compound: 2-(3-fluorobenzamido)-N-[3-(morpholin-4-yl)propyl]-1,3-thiazole-4-carboxamide
V014-4270 Screening compound: 2-(3-fluorobenzamido)-N-[3-(morpholin-4-yl)propyl]-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-4270
2-(3-fluorobenzamido)-N-[3-(morpholin-4-yl)propyl]-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-4270

Molecular Formula

C18H21FN4O3S (C18 H21 FN4 O3 S)

Compound Name

2-(3-fluorobenzamido)-N-[3-(morpholin-4-yl)propyl]-1,3-thiazole-4-carboxamide

IUPAC name

2-(3-fluorobenzamido)-N-[3-(morpholin-4-yl)propyl]-13-thiazole-4-carboxamide

SMILES

O=C(c1csc(NC(c2cc(F)ccc2)=O)n1)NCCCN1CCOCC1

InChI

InChI=1S/C18H21FN4O3S/c19-14-4-1-3-13(11-14)16(24)22-18-21-15(12-27-18)17(25)20-5-2-6-23-7-9-26-10-8-23/h1,3-4,11-12H,2,5-10H2,(H,20,25)(H,21,22,24)

InChI Key

AJUVZRDOGSTFHE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19975683

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

392.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.910

Distribution Coefficient, logD

1.910

Water Solubility, LogSw

-2.64

Polar Surface Area

69.522

Acid Dissociation Constant (pKa)

6.67

Base Dissociation Constant (pKb)

7.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

V014-4270 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

PI3K-Targeted Library (17255 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with V014-4270 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-4270?
Check Price and Availability of V014-4270, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V014-4270 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-4270
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-4270
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-4270 available by request