V014-5440 Screening compound: N-(6-{4-[2-(4-chlorophenoxy)acetyl]piperazin-1-yl}pyridin-3-yl)-2-methylbenzamide

V014-5440 Screening compound: N-(6-{4-[2-(4-chlorophenoxy)acetyl]piperazin-1-yl}pyridin-3-yl)-2-methylbenzamide
V014-5440 Screening compound: N-(6-{4-[2-(4-chlorophenoxy)acetyl]piperazin-1-yl}pyridin-3-yl)-2-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-5440
N-(6-{4-[2-(4-chlorophenoxy)acetyl]piperazin-1-yl}pyridin-3-yl)-2-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-5440

Molecular Formula

C25H25ClN4O3 (C25 H25 ClN4 O3)

Compound Name

N-(6-{4-[2-(4-chlorophenoxy)acetyl]piperazin-1-yl}pyridin-3-yl)-2-methylbenzamide

IUPAC name

N-(6-{4-[2-(4-chlorophenoxy)acetyl]piperazin-1-yl}pyridin-3-yl)-2-methylbenzamide

SMILES

Cc(cccc1)c1C(Nc(cc1)cnc1N(CC1)CCN1C(COc(cc1)ccc1Cl)=O)=O

InChI

InChI=1S/C25H25ClN4O3/c1-18-4-2-3-5-22(18)25(32)28-20-8-11-23(27-16-20)29-12-14-30(15-13-29)24(31)17-33-21-9-6-19(26)7-10-21/h2-11,16H,12-15,17H2,1H3,(H,28,32)

InChI Key

COQNONRZFQTAPW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19898708

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

464.95

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.266

Distribution Coefficient, logD

4.264

Water Solubility, LogSw

-4.53

Polar Surface Area

58.811

Acid Dissociation Constant (pKa)

10.08

Base Dissociation Constant (pKb)

4.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

V014-5440 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with V014-5440 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-5440?
Check Price and Availability of V014-5440, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V014-5440 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-5440
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-5440
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-5440 available by request